Cell-cycle signaling: Atm displays its many talents

نویسنده

  • Christoph Heiner Westphal
چکیده

The discovery of multiple signaling cascades downstream of Atm may lead to a clearer understanding of the diverse defects seen in ataxia-telangiectasia. These pathways - which include evolutionarily conserved Chk1 and Atr, and non-conserved p21, p53 and AbI - guard genomic integrity after DNA damage.

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عنوان ژورنال:
  • Current Biology

دوره 7  شماره 

صفحات  -

تاریخ انتشار 1997